How It Works
Psilocybin interacts with the brain’s serotonin 2A receptors, which play a key role in mood, perception, and cognition.
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*Balances serotonin: Low levels are linked to anxiety and depression. Psilocybin helps restore balance.
*Boosts neuroplasticity: Encourages the brain to form new pathways, supporting mental flexibility and healing.
*Fosters openness: Some users report spiritual insight and emotional breakthroughs.
*Long-term effects: Studies show even a single guided dose can ease depression and anxiety for months.

How to Start Microdosing
Be patient: Microdosing is subtle — results build over time.
1. Pick a start date and set a clear intention
2. Choose a protocol (e.g., Fadiman or Stamets)
3. Start small: 50mg is common for beginners
4. Increase slowly in 10mg steps if needed
5. Reflect and journal after each dose
6. Dose in the morning to avoid sleep disruptions

If You're on Antidepressants
Psychedelics and antidepressants can interact in important ways. Here are some things to consider:
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*SSRIs & SNRIs (like Prozac or Cymbalta) may dampen the effects of psilocybin. This can continue weeks after stopping the meds.
*TCAs (like amitriptyline) may amplify psychedelic effects due to different mechanisms.
*Bupropion (Wellbutrin), which doesn’t target serotonin, seems to have minimal interference.

Microdosing is not a magic fix — but it may be a powerful tool for enhancing emotional well-being and cognitive clarity. With intention, patience, and the right approach, it can open the door to meaningful change.

Always consult a healthcare provider before mixing medications with psychedelics.